QExactive High-Resolution Mass Spectrometer

The QExactive (quadrupole-Orbitrap) mass spectrometer is coupled to an Equan Max Plus automated solid phase extraction (SPE) system and a Dionex high-performance liquid chromatography (HPLC) system.  We use the QExactive to develop novel methods to assess the occurrence of trace organic contaminants in aquatic environments and to elucidate chemical structures of reaction intermediates and endpoints.

QExactive coupled to an EASY-nanoLC 1000 UHPLC system

We use this system to explore the world of environmental proteomics.  We isolate and quantify protein biomarkers that are predictive of biodegradation processes and attempt to identify unknown proteins involved in biotransformation reactions.

UltiMate 3000 HPLC system coupled to a Variable Wavelength UV-Vis Detector and Automated Fraction Collector

We use this system as an analytical tool to measure the concentrations of organic chemicals in aqueous solution and characterize the kinetics of reaction processes.  We also use this system as a semi-preparative tool to isolate and collect transformation intermediates or endpoints for subsequent structure elucidation by means of high-resolution mass spectrometry and/or nuclear magnetic resonance.